pentobarbital will lessen the extent or impact of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Outcome of coadministering a solid CYP3A4 inducer with fedratinib hasn't been researched.pentobarbital will lower the extent or influence of carvedilol by influencing hepatic enzyme CYP2C9/ten metabol… Read More